While the exact mechanism of navicular disease is not fully understood, we do know that as part of the disease process, the normal metabolism of the navicular bone is disturbed. Excessive bone resorption or abnormal mineralization of the bone leads to the characteristic changes seen on radiographs, overall bone weakness and inflammation involving associated structures in the back of the hoof.
Tildren is a commonly used treatment for those horses suffering from the early stages of navicular disease. Tiludronate belongs to the bisphosphonate family of drugs and can help normalize the metabolism of bone by preventingfurther resorption and analgesic (pain relief) properties. Tildren is administered in a diluted form in fluids over 2-3 hours and can be done as an outpatient procedure at the hospital.